Comprehensive host-pathogen protein-protein interaction network analysis

Protein Disulfide Isomerase and Host-Pathogen Interaction

Reactive oxygen species (ROS) production by immunological cells is known to cause damage to pathogens. Increasing evidence accumulated in the last decade has shown, however, that ROS (and redox signals) functionally regulate different cellular pathways in the host-pathogen interaction. These especially affect (i) pathogen entry through protein redox switches and redox modification (i.e., intra-...

protein-protein interaction network analysis of cirrhosis liver disease

aim : evaluation of biological characteristics of 13 identified proteins of patients with cirrhotic liver disease is the main aim of this research.   background : in clinical usage, liver biopsy remains the gold standard for diagnosis of hepatic fibrosis. evaluation and confirmation of liver fibrosis stages and severity of chronic diseases require a precise and noninvasive biomarkers. since the...

Training large margin host-pathogen protein-protein interaction predictors

ABDUL HANNAN BASIT, WAJID ARSHAD ABBASI, AMINA ASIF, AND FAYYAZ UL AMIR AFSAR MINHAS † Biomedical Informatics Research Laboratory, Department of Computer and Information Sciences, Pakistan Institute of Engineering and Applied Sciences (PIEAS), Nilore, Islamabad, Pakistan Department of Electrical Engineering, Pakistan Institute of Engineer-ing and Applied Sciences (PIEAS), Nilore, Islamabad, 440...

protein-protein interaction network of celiac disease

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Towards a comprehensive human protein-protein interaction network